Effect of Strain Rate on Single Tau, Dimerized Tau and Tau-Microtubule Interface: A Molecular Dynamics Simulation Study

Microtubule-associated protein (MAP) tau is a cross-linking molecule that provides structural stability to axonal microtubules (MT). It is considered a potential biomarker for Alzheimer’s disease (AD), dementia, and other neurological disorders. It is also a signature protein for Traumatic Brain Inj...

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Bibliographic Details
Main Authors: Md Ishak Khan, Kathleen Gilpin, Fuad Hasan, Khandakar Abu Hasan Al Mahmud, Ashfaq Adnan
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/9/1308