Synthesis of L-asparagine Catalyzed by a Novel Asparagine Synthase Coupled With an ATP Regeneration System

Synthesis of L-asparagine Catalyzed by a Novel Asparagine Synthase Coupled With an ATP Regeneration System

Compared with low-yield extraction from plants and environmentally unfriendly chemical synthesis, biocatalysis by asparagine synthetase (AS) for preparation of L-asparagine (L-Asn) has become a potential synthetic method. However, low enzyme activity of AS and high cost of ATP in this reaction restr...

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Bibliographic Details
Main Authors: Wei Luo, Jinglong Xu, Huiying Chen, Huili Zhang, Peilong Yang, Xiaobin Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
l-Asparagine
asparagine synthase
class III polyphosphate kinase
ATP regeneration system
biocatalysis and biotransformation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.747404/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.747404/full

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