Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

Abstract Background Glioblastoma (GBM) are highly heterogeneous on the cellular and molecular basis. It has been proposed that glutamine metabolism of primary cells established from human tumors discriminates aggressive mesenchymal GBM subtype to other subtypes. Methods To study glutamine metabolism...

Full description

Bibliographic Details
Main Authors: Kristell Oizel, Chendong Yang, Ophelie Renoult, Fabien Gautier, Quyen N. Do, Noemie Joalland, Xiaofei Gao, Bookyung Ko, François Vallette, Woo-Ping Ge, François Paris, Ralph J. DeBerardinis, Claire Pecqueur
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cancer & Metabolism
Subjects:
Glioblastoma
Metabolism
Molecular subtype
Mesenchymal
Glutamine
Human primary cells
Online Access:http://link.springer.com/article/10.1186/s40170-020-00215-8

Internet

http://link.springer.com/article/10.1186/s40170-020-00215-8

Similar Items