Delivery of microRNA-33 Antagomirs by Mesoporous Silica Nanoparticles to Ameliorate Lipid Metabolic Disorders

Delivery of microRNA-33 Antagomirs by Mesoporous Silica Nanoparticles to Ameliorate Lipid Metabolic Disorders

Lipid metabolic disorders have become a major global public health concern. Fatty liver and dyslipidemia are major manifestations of these disorders. Recently, MicroRNA-33 (miR-33), a post-transcriptional regulator of genes involved in cholesterol efflux and fatty acid oxidation, has been considered...

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Bibliographic Details
Main Authors: Yaoye Tao, Shengjun Xu, Jianguo Wang, Li Xu, Chenzhi Zhang, Kangchen Chen, Zhengxing Lian, Junbin Zhou, Haiyang Xie, Shusen Zheng, Xiao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
mesoporous silica nanoparticles
lipid metabolic disorder
non-alcoholic fatty liver disease
dyslipidemia
miR-33
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00921/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00921/full

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