Triptans and CGRP blockade – impact on the cranial vasculature

Triptans and CGRP blockade – impact on the cranial vasculature

Abstract The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide (CGRP), which modulate pain transmission an...

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Bibliographic Details
Main Authors: Silvia Benemei, Francesca Cortese, Alejandro Labastida-Ramírez, Francesca Marchese, Lanfranco Pellesi, Michele Romoli, Anne Luise Vollesen, Christian Lampl, Messoud Ashina, On behalf of the School of Advanced Studies of the European Headache Federation (EHF-SAS)
Format: Article
Language:English
Published: BMC 2017-10-01
Series:The Journal of Headache and Pain
Subjects:
Triptans
Calcitonin gene related peptide – CGRP
Anti-CGRP (receptor) monoclonal antibodies – mAbs
Middle meningeal artery
Middle cerebral arteries
Migraine models
Online Access:http://link.springer.com/article/10.1186/s10194-017-0811-5

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http://link.springer.com/article/10.1186/s10194-017-0811-5

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