Coordination of EZH2 and SOX2 specifies human neural fate decision

Coordination of EZH2 and SOX2 specifies human neural fate decision

Abstract Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this study, by employing an array of different approaches, such as gene knock-out, RNA-seq,...

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Bibliographic Details
Main Authors: Yuan Zhao, Tianyu Wang, Yanqi Zhang, Liang Shi, Cong Zhang, Jingyuan Zhang, Jiao Yao, Qianyu Chen, Xiaofen Zhong, Yanxing Wei, Yongli Shan, Guangjin Pan
Format: Article
Language:English
Published: SpringerOpen 2021-09-01
Series:Cell Regeneration
Online Access:https://doi.org/10.1186/s13619-021-00092-6

Internet

https://doi.org/10.1186/s13619-021-00092-6

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