Coordination of EZH2 and SOX2 specifies human neural fate decision
Abstract Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this study, by employing an array of different approaches, such as gene knock-out, RNA-seq,...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2021-09-01
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| Series: | Cell Regeneration |
| Online Access: | https://doi.org/10.1186/s13619-021-00092-6 |