Choice of cell-delivery route for skeletal myoblast transplantation for treating post-infarction chronic heart failure in rat.

BACKGROUND:Intramyocardial injection of skeletal myoblasts (SMB) has been shown to be a promising strategy for treating post-infarction chronic heart failure. However, insufficient therapeutic benefit and occurrence of ventricular arrhythmias are concerns. We hypothesised that the use of a retrograd...

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Bibliographic Details
Main Authors: Satsuki Fukushima, Steven R Coppen, Joon Lee, Kenichi Yamahara, Leanne E Felkin, Cesare M N Terracciano, Paul J R Barton, Magdi H Yacoub, Ken Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2516937?pdf=render