A Probabilistic Approach to Explore Signal Execution Mechanisms With Limited Experimental Data

Mathematical models of biochemical reaction networks are central to the study of dynamic cellular processes and hypothesis generation that informs experimentation and validation. Unfortunately, model parameters are often not available and sparse experimental data leads to challenges in model calibra...

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Bibliographic Details
Main Authors: Michael A. Kochen, Carlos F. Lopez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00686/full