Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

Objective: A potential strategy to treat obesity – and the associated metabolic consequences – is to increase energy expenditure. This could be achieved by stimulating thermogenesis through activation of brown adipose tissue (BAT) and/or the induction of browning of white adipose tissue (WAT). Over...

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Bibliographic Details
Main Authors: Dries Bauters, Mathias Cobbaut, Lotte Geys, Johan Van Lint, Bianca Hemmeryckx, H. Roger Lijnen
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Molecular Metabolism
Subjects:
ADAMTS5
Brown adipose tissue
Browning
Beige
Thermogenesis
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817302818

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http://www.sciencedirect.com/science/article/pii/S2212877817302818

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