CX691 as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer’s disease

CX691 as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer’s disease

Objective(s): Growing evidence suggests that dysfunction of the glutamatergic system and α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptors are involved in pathology of Alzheimer’s disease (AD). Because AMPA receptors play a key role in plasticity synaptic regulation, positive modu...

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Bibliographic Details
Main Authors: Nazanin Mozafari, Ali Shamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Amir Moghadam-Ahmadi, Elham Kaviani, Ayat Kaeidi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-07-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Alzheimer’s disease
AMPA receptors
BDNF
CX691
Memory
Rat
Online Access:http://ijbms.mums.ac.ir/article_10760_8bdeb1455cbdce80a0dc8c5f31b64d8e.pdf

Internet

http://ijbms.mums.ac.ir/article_10760_8bdeb1455cbdce80a0dc8c5f31b64d8e.pdf

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