Safety and feasibility of long-term intravenous sodium nitrite infusion in healthy volunteers.

Infusion of sodium nitrite could provide sustained therapeutic concentrations of nitric oxide (NO) for the treatment of a variety of vascular disorders. The study was developed to determine the safety and feasibility of prolonged sodium nitrite infusion.Healthy volunteers, aged 21 to 60 years old, w...

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Bibliographic Details
Main Authors: Ryszard M Pluta, Edward H Oldfield, Kamran D Bakhtian, Ali Reza Fathi, René K Smith, Hetty L Devroom, Masoud Nahavandi, Sukyung Woo, William D Figg, Russell R Lonser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3018414?pdf=render