Design of Agglomerated Crystals of Ibuprofen During Crystallization: Influence of Surfactant

Objective(s)Ibuprofen is a problematic drug in tableting, and dissolution due to its poor solubility, hydrophobicity, and tendency to stick to surface. Because of the bad compaction behavior ibuprofen has to be granulated usually before tableting. However, it would be more satisfactory to obtain dir...

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Bibliographic Details
Main Authors: Maryam Maghsoodi, Leila Barghi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2011-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://www.mums.ac.ir/shares/basic_medical/basicmedjou/89/winter/a8.pdf