Opposite modulation of brain stimulation reward by NMDA and AMPA receptors in the ventral tegmental area.

Opposite modulation of brain stimulation reward by NMDA and AMPA receptors in the ventral tegmental area.

Previous studies have shown that blockade of ventral midbrain (VM) glutamate N-Methyl-D-Aspartate (NMDA) receptors induces reward, stimulates forward locomotion and enhances brain stimulation reward. Glutamate induces two types of excitatory response on VM neurons, a fast and short lasting depolaris...

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Bibliographic Details
Main Authors: Charles eDucrot, Emmanuel eFortier, Claude eBouchard, Pierre Paul eRompre
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Glutamate
NMDA
Reward
AMPA
ventral midbrain.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00057/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00057/full

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