Optimization and development of insulin nanoparticles by new thiolated chitosan derivative with ionic gelation method using a model-based methodology
Insulin therapy has been the best choice for the clinical management of diabetes mellitus. The current insulin therapy is via subcutaneous injection, which often fails to mimic the glucose homeostasis that occurs in normal individuals. Oral delivery is the most convenient administration route. Howev...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
University of Tehran
2019-06-01
|
Series: | Journal of Food and Bioprocess Engineering |
Subjects: | |
Online Access: | https://jfabe.ut.ac.ir/article_73075_dac7632abdef522b0aecf29bd9b9c6d4.pdf |