Mutational load in carotid body tumor

Mutational load in carotid body tumor

Abstract Background Carotid body tumor (CBT) is a rare neoplasm arising from paraganglion located near the bifurcation of the carotid artery. There is great intra-tumor heterogeneity, and CBT development could be associated with both germline and somatic allelic variants. Studies on the molecular ge...

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Bibliographic Details
Main Authors: Anna V. Kudryavtseva, Elena N. Lukyanova, Dmitry V. Kalinin, Andrew R. Zaretsky, Anatoly V. Pokrovsky, Alexander L. Golovyuk, Maria S. Fedorova, Elena A. Pudova, Sergey L. Kharitonov, Vladislav S. Pavlov, Anastasiya A. Kobelyatskaya, Nataliya V. Melnikova, Alexey A. Dmitriev, Andrey P. Polyakov, Boris Y. Alekseev, Marina V. Kiseleva, Andrey D. Kaprin, George S. Krasnov, Anastasiya V. Snezhkina
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medical Genomics
Subjects:
Carotid body tumor
Mutational load
Somatic variants
Germline variants
Exome
High-throughput sequencing
Online Access:http://link.springer.com/article/10.1186/s12920-019-0483-x

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http://link.springer.com/article/10.1186/s12920-019-0483-x

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