Cytotoxicity of Some Nitroimidazole Derivatives - Comparative Studies on Human and Rat Hepatoma Cell Lines

The cytototoxic potential of metronidazole, tinidazole, ronidazole, and ornidazole, using human and rat hepatoma cell lines (HepG2 and FaO) in culture was assessed. The cells were treated with drugs for 24, 48 and 72 h at 37 °C in 5% CO2 at concentrations of 0.1 to 200 μg/mL. Following the treatment...

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Bibliographic Details
Main Authors: Radko Lidia, Minta Maria
Format: Article
Language:English
Published: Sciendo 2012-12-01
Series:Bulletin of the Veterinary Institute in Pulawy
Subjects:
Online Access:https://doi.org/10.2478/v10213-012-0102-5