Low CXCL13 expression, splenic lymphoid tissue atrophy and germinal center disruption in severe canine visceral leishmaniasis.

Low CXCL13 expression, splenic lymphoid tissue atrophy and germinal center disruption in severe canine visceral leishmaniasis.

Visceral leishmaniasis is associated with atrophy and histological disorganization of splenic compartments. In this paper, we compared organized and disorganized splenic lymphoid tissue from dogs naturally infected with Leishmania infantum assessing the size of the white pulp compartments, the distr...

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Bibliographic Details
Main Authors: Joselli S Silva, Alan C Andrade, Claudia C Santana, Leina Q Santos, Camila I de Oliveira, Patrícia S T Veras, José Vassallo, Washington L C dos-Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3252310?pdf=render

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http://europepmc.org/articles/PMC3252310?pdf=render

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