Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro

Variation in methotrexate (MTX) efficacy represents a significant barrier to early and effective disease control in the treatment of autoimmune arthritis. We hypothesize that the utilization of metabolomic techniques will allow for an improved understanding of the biochemical basis for the pharmacol...

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Bibliographic Details
Main Authors: Ryan S. Funk, Rakesh K. Singh, Mara L. Becker
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12694