Enhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation

Enhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation

Vascularization is a common pathology for many solid tumors, and therefore anti-angiogenic strategies are being investigated as a therapeutic target for treatment. Numerous studies are also being conducted regarding the effects of oncolytic viruses, including Imlygic<sup>TM</sup>, an FDA...

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Bibliographic Details
Main Authors: Mitra Nair, Maninder Khosla, Yoshihiro Otani, Margaret Yeh, Flora Park, Toshihiko Shimizu, Jin Muk Kang, Chelsea Bolyard, Jun-Ge Yu, Yeshavanth Kumar Banasavadi-Siddegowda, Gonzalo Lopez, Balveen Kaur, Raphael E. Pollock, Tae Jin Lee, Matthew Old, Ji Young Yoo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
oncolytic herpes simplex virus-1 (oHSV)
soft tissue sarcoma (STS)
rapid antiangiogenesis mediated by oncolytic virus (RAMBO)
angiogenesis
vasculostatin (Vstat120)
tumor microenvironment (TME)
Online Access:https://www.mdpi.com/2072-6694/12/4/1040

Internet

https://www.mdpi.com/2072-6694/12/4/1040

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