Antiproliferative <i>S</i>-Trityl-<span style="font-variant: small-caps">l</span>-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement

Antiproliferative <i>S</i>-Trityl-<span style="font-variant: small-caps">l</span>-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement

<i>S</i>-trityl-<span style="font-variant: small-caps;">l</span>-cysteine (<b>STLC</b>) is a well-recognized lead compound known for its anticancer activity owing to its potent inhibitory effect on human mitotic kinesin Eg5. <b>STLC</b> conta...

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Bibliographic Details
Main Authors: Mohamed O. Radwan, Halil I. Ciftci, Taha F. S. Ali, Doha E. Ellakwa, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
<b>STLC</b>
SIRT2
anticancer
molecular docking
solubility
Online Access:https://www.mdpi.com/1420-3049/24/18/3295

Internet

https://www.mdpi.com/1420-3049/24/18/3295

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