Reduced Alcohol Seeking and Withdrawal Symptoms in Mice Lacking the BDNF Receptor SorCS2

Reduced Alcohol Seeking and Withdrawal Symptoms in Mice Lacking the BDNF Receptor SorCS2

Alcohol use disorder (AUD) is characterized by repetitive and uncontrolled intake of alcohol with severe consequences for affected individuals, their families and society as a whole. Numerous studies have implicated brain-derived neurotrophic factor (BDNF) activity in the neurobiology underlying AUD...

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Bibliographic Details
Main Authors: Ditte Olsen, Mathias Kaas, Jesper Lundhede, Simon Molgaard, Anders Nykjær, Mads Kjolby, Søren D. Østergaard, Simon Glerup
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
SorCS2
alcohol
alcohol use disorder
alcohol withdrawal
BDNF and VPS10p-domain receptor
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00499/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00499/full

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