Rapid turnover of long noncoding RNAs and the evolution of gene expression.

A large proportion of functional sequence within mammalian genomes falls outside protein-coding exons and can be transcribed into long RNAs. However, the roles in mammalian biology of long noncoding RNA (lncRNA) are not well understood. Few lncRNAs have experimentally determined roles, with some of...

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Bibliographic Details
Main Authors: Claudia Kutter, Stephen Watt, Klara Stefflova, Michael D Wilson, Angela Goncalves, Chris P Ponting, Duncan T Odom, Ana C Marques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3406015?pdf=render