Targeted Metabolic Profiling of Urine Highlights a Potential Biomarker Panel for the Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment: A Pilot Study

Targeted Metabolic Profiling of Urine Highlights a Potential Biomarker Panel for the Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment: A Pilot Study

The lack of sensitive and specific biomarkers for the early detection of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is a major hurdle to improving patient management. A targeted, quantitative metabolomics approach using both <sup>1</sup>H NMR and mass spectrometry was e...

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Bibliographic Details
Main Authors: Ali Yilmaz, Zafer Ugur, Halil Bisgin, Sumeyya Akyol, Ray Bahado-Singh, George Wilson, Khaled Imam, Michael E. Maddens, Stewart F. Graham
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Metabolites
Subjects:
Alzheimer’s disease
mild cognitive impairment
metabolomics
urine
biomarkers
machine learning
Online Access:https://www.mdpi.com/2218-1989/10/9/357

Internet

https://www.mdpi.com/2218-1989/10/9/357

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