The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, highlighting a potential for β-mannan-based therapeutic...

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Bibliographic Details
Main Authors: Sabina Leanti La Rosa, Maria Louise Leth, Leszek Michalak, Morten Ejby Hansen, Nicholas A. Pudlo, Robert Glowacki, Gabriel Pereira, Christopher T. Workman, Magnus Ø. Arntzen, Phillip B. Pope, Eric C. Martens, Maher Abou Hachem, Bjørge Westereng
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08812-y