Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.

Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.

<h4>Introduction</h4>Germline BRCA1 or BRCA2 mutations account for 20-30% of familial clustering of breast cancer. The main indication for BRCA2 screening is currently the family history but the yield of mutations identified in patients selected this way is low.<h4>Methods</h4&g...

Full description

Bibliographic Details
Main Authors: Audrey Rouault, Guillaume Banneau, Gaëtan Macgrogan, Natalie Jones, Nabila Elarouci, Emmanuelle Barouk-Simonet, Laurence Venat, Isabelle Coupier, Eric Letouzé, Aurélien de Reyniès, Françoise Bonnet, Richard Iggo, Nicolas Sévenet, Michel Longy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284877/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284877/?tool=EBI

Similar Items