A Framework for Effective Application of Machine Learning to Microbiome-Based Classification Problems

Diagnosing diseases using machine learning (ML) is rapidly being adopted in microbiome studies. However, the estimated performance associated with these models is likely overoptimistic. Moreover, there is a trend toward using black box models without a discussion of the difficulty of interpreting su...

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Bibliographic Details
Main Authors: Begüm D. Topçuoğlu, Nicholas A. Lesniak, Mack T. Ruffin, Jenna Wiens, Patrick D. Schloss
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00434-20