Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells
Abstract Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have ana...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-11-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-16590-0 |