Increased NK Cell Count in Multiple Sclerosis Patients Treated With Dimethyl Fumarate: A 2-Year Longitudinal Study

Increased NK Cell Count in Multiple Sclerosis Patients Treated With Dimethyl Fumarate: A 2-Year Longitudinal Study

Background: Dimethyl fumarate (DMF) is a disease-modifying drug for relapsing-remitting multiple sclerosis. Among others, DMF impedes immune activation by shifting the balance between inflammatory and regulatory cell types and by inducing apoptosis-triggered lymphopenia. Although the decrease in lym...

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Bibliographic Details
Main Authors: Damiano Marastoni, Alessandro Buriani, Anna Isabella Pisani, Francesco Crescenzo, Carmela Zuco, Stefano Fortinguerra, Vincenzo Sorrenti, Bruno Marenda, Chiara Romualdi, Roberta Magliozzi, Salvatore Monaco, Massimiliano Calabrese
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
dimethyl fumarate
lymphopenia
natural killer cells
cell count
lymphocyte subsets
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01666/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01666/full

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