Memantine Enhances the Effect of Olanzapine in Patients With Schizophrenia: A Randomized, Placebo-Controlled Study

Memantine Enhances the Effect of Olanzapine in Patients With Schizophrenia: A Randomized, Placebo-Controlled Study

Glutamate dysregulation may be involved in the neuropathology of schizophrenia. Memantine, a drug approved by the FDA for the treatment of moderate to severe Alzheimer's disease, acts as a partial uncompetitive NMDA receptor antagonist. The aim of this study was to examine the efficacy of mema...

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Bibliographic Details
Main Authors: Ahmad Fakhri, Sirous Pakseresht, Mohammad Reza Haghdoost, Nasihat Hekmatkhah, Maria Torkashvand, Behnam Ghorbanzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-12-01
Series:Acta Medica Iranica
Subjects:
Memantine
Schizophrenia
Combination therapy
Gender
NMDA receptors
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/5105

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/5105

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