Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors.

Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors.

Mechanical forces play a crucial role in tumor patho-physiology. Compression of cancer cells inhibits their proliferation rate, induces apoptosis and enhances their invasive and metastatic potential. Additionally, compression of intratumor blood vessels reduces the supply of oxygen, nutrients and dr...

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Bibliographic Details
Main Authors: Chrysovalantis Voutouri, Fotios Mpekris, Panagiotis Papageorgis, Andreani D Odysseos, Triantafyllos Stylianopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4128744?pdf=render

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http://europepmc.org/articles/PMC4128744?pdf=render

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