Phosphatidylinositol Inhibits Vascular Endothelial Growth Factor-A–Induced Migration of Human Umbilical Vein Endothelial Cells

Phosphatidylinositol (PI), a phospholipid in component of cell membranes, is widely distributed in animals, plants, and microorganisms. Here, we examined in vitro whether PI inhibits the angiogenesis induced by vascular endothelial growth factor-A (VEGF-A). PI concentration-relatedly and significant...

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Bibliographic Details
Main Authors: Nozomu Matsunaga, Masamitsu Shimazawa, Kazumasa Otsubo, Hideaki Hara
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319315452