Factor XII – What's important but not commonly thought about

Abstract Factor XII (FXII) becomes a serine protease when blood is exposed to artificial medical surfaces or when pathologic surfaces arise in disease states leading to its autoactivation. Initiation of the blood coagulation cascade was the first recognized activity of FXIIa. Blocking FXIIa activity...

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Bibliographic Details
Main Authors: Alvin H. Schmaier, Evi X. Stavrou
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12235