TRAF3 regulates homeostasis of CD8+ central memory T cells.

Our laboratory reported previously that TNF receptor associated factor 3 (TRAF3) is a positive regulator of TCR signaling and T cell function. In the current study, we present new findings that reveal differential roles for TRAF3 in the regulation of CD4+ and CD8(+) T cells. In response to TCR stimu...

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Bibliographic Details
Main Authors: Zuoan Yi, Laura L Stunz, Wai Wai Lin, Gail A Bishop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4092107?pdf=render