A constrained polynomial regression procedure for estimating the local False Discovery Rate

<p>Abstract</p> <p>Background</p> <p>In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (<it>lFDR</it>), which quantifies the evidence of a specific gene a...

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Bibliographic Details
Main Authors: Broët Philippe, Bar-Hen Avner, Dalmasso Cyril
Format: Article
Language:English
Published: BMC 2007-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/229