Prodrug Approach for Increasing Cellular Glutathione Levels

Reduced glutathione (GSH) is the most abundant non-protein thiol in mammalian cells and the preferred substrate for several enzymes in xenobiotic metabolism and antioxidant defense. It plays an important role in many cellular processes, such as cell differentiation, proliferation and apoptosis. GSH...

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Bibliographic Details
Main Authors: Ivana Cacciatore, Catia Cornacchia, Francesco Pinnen, Adriano Mollica, Antonio Di Stefano
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/3/1242/