The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice

The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice

Obesity and diabetes are major causes of morbidity and mortality globally. The current study builds upon our previous association studies highlighting that A Disintegrin And Metalloproteinase 28 (ADAM28) appears to be implicated in the pathogenesis of obesity and type 2 diabetes in humans. Our novel...

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Bibliographic Details
Main Authors: Lakshini Herat, Caroline Rudnicka, Yasunori Okada, Satsuki Mochizuki, Markus Schlaich, Vance Matthews
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
ADAM28
type 2 diabetes (T2D)
obesity
metabolic syndrome
metalloproteinases
Online Access:http://www.mdpi.com/1422-0067/18/4/884

Internet

http://www.mdpi.com/1422-0067/18/4/884

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