Association of TREM-1, IL-1β, IL-33/ST2, and TLR Expressions With the Pathogenesis of Ocular Toxoplasmosis in Mouse Models on Different Genetic Backgrounds

Association of TREM-1, IL-1β, IL-33/ST2, and TLR Expressions With the Pathogenesis of Ocular Toxoplasmosis in Mouse Models on Different Genetic Backgrounds

Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like recepto...

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Bibliographic Details
Main Authors: Yanxia Zhang, Jian He, Huanqin Zheng, Shiguang Huang, Fangli Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
ocular toxoplasmosis
C57BL/6 mice
BALB/c mice
TREM-1
IL-1β
IL-33/ST2
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02264/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02264/full

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