Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome

Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome

Inflammation is typically related to dysfunction of the blood-brain barrier (BBB) that leads to early brain injury (EBI) after subarachnoid hemorrhage (SAH). Resolvin D1 (RVD1), a lipid mediator derived from docosahexaenoic acid, possesses anti-inflammatory and neuroprotective properties. This study...

Full description

Bibliographic Details
Main Authors: Chengcong Wei, Shenquan Guo, Wenchao Liu, Fa Jin, Boyang Wei, Haiyan Fan, Hengxian Su, Jiahui Liu, Nan Zhang, Dazhao Fang, Guangxu Li, Shixing Shu, Xifeng Li, Xuying He, Xin Zhang, Chuanzhi Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
resolvin D1
A20
NLRP3 inflammasome
blood-brain barrier
inflammation
subarachnoid hemorrhage
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.610734/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.610734/full

Similar Items