Endothelial Function in a Mouse Model of Myeloperoxidase Deficiency

Myeloperoxidase (MPO) activity is suggested to reduce the function of vascular nitric oxide, thereby contributing to endothelial dysfunction, although data in rodents are inconclusive. We examined vascular contractile and relaxant responses in MPO-deficient (MPO-/-) and wild-type mice to investigate...

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Bibliographic Details
Main Authors: Veronika Golubinskaya, Ulla Brandt-Eliasson, Li-Ming Gan, Martin Kjerrulf, Holger Nilsson
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/128046