Reversal of the ΔdegP phenotypes by a novel rpoE allele of Escherichia coli.

RseA sequesters RpoE (σ(E)) to the inner membrane of Escherichia coli when envelope stress is low. Elevated envelope stress triggers RseA cleavage by the sequential action of two membrane proteases, DegS and RseP, releasing σ(E) to activate an envelope stress reducing pathway. Revertants of a ΔdegP...

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Bibliographic Details
Main Authors: Owen P Leiser, Emily S Charlson, Henri Gerken, Rajeev Misra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3306311?pdf=render