Effect of MDMA-Induced Axotomy on the Dorsal Raphe Forebrain Tract in Rats: An In Vivo Manganese-Enhanced Magnetic Resonance Imaging Study.

3,4-Methylenedioxymethamphetamine (MDMA), also known as "Ecstasy", is a common recreational drug of abuse. Several previous studies have attributed the central serotonergic neurotoxicity of MDMA to distal axotomy, since only fine serotonergic axons ascending from the raphe nucleus are lost...

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Bibliographic Details
Main Authors: Chuang-Hsin Chiu, Tiing-Yee Siow, Shao-Ju Weng, Yi-Hua Hsu, Yuahn-Sieh Huang, Kang-Wei Chang, Cheng-Yi Cheng, Kuo-Hsing Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574734?pdf=render