Feeder-free generation and transcriptome characterization of functional mesenchymal stromal cells from human pluripotent stem cells

Feeder-free generation and transcriptome characterization of functional mesenchymal stromal cells from human pluripotent stem cells

Induced mesenchymal stromal cells (iMSCs) derived from human pluripotent stem cells (PSCs) are attractive cells for regenerative medicine. However, the transcriptome of iMSCs and signature genes that can distinguish MSCs from fibroblasts and other cell types are rarely explored. In this study, we re...

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Bibliographic Details
Main Authors: Lidan Luo, Yan Zhou, Chenxi Zhang, Jinrong Huang, Jie Du, Jinqi Liao, Natasja Leth Bergholt, Cody Bünger, Fengping Xu, Lin Lin, Guangdong Tong, Guangqian Zhou, Yonglun Luo
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Stem Cell Research
Subjects:
Mesenchymal stromal cells
Pluripotent stem cells
Induced mesenchymal stromal cells (iMSCs)
Transcriptome
Marker
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120302919

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http://www.sciencedirect.com/science/article/pii/S1873506120302919

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