MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells.

Chronic lymphocytic leukemia (CLL) is thought to be a disease of resting lymphocytes. However, recent data suggest that CLL cells may more closely resemble activated B cells. Using microRNA (miRNA) expression profiling of highly-enriched CLL cells from 38 patients and 9 untransformed B cells from no...

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Bibliographic Details
Main Authors: Shuqiang Li, Howell F Moffett, Jun Lu, Lillian Werner, Hao Zhang, Jerome Ritz, Donna Neuberg, Kai W Wucherpfennig, Jennifer R Brown, Carl D Novina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3050979?pdf=render