Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

Abstract Adult mesenchymal stem cells exert immunomodulatory effects that might improve the host response during sepsis. Knowledge on the effect of adipose‐derived mesenchymal stem cells (ASCs) in sepsis is limited. Klebsiella (K.) pneumoniae is a common cause of gram‐negative pneumonia and sepsis....

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Bibliographic Details
Main Authors: Desiree Perlee, Alex F. deVos, Brendon P. Scicluna, Pablo Mancheño, Olga de laRosa, Wilfried Dalemans, Peter Nürnberg, Eleuterio Lombardo, Tom van derPoll
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Stem Cells Translational Medicine
Subjects:
Pneumonia
Sepsis
Mesenchymal stem cells
Immunomodulation
Online Access:https://doi.org/10.1002/sctm.18-0260

Internet

https://doi.org/10.1002/sctm.18-0260

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