Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage

These studies were undertaken to characterize the role of plasma membrane cholesterol in canalicular secretory functions and hepatocyte integrity against intravenous taurocholate administration. Cholesterol and sphingomyelin concentrations and cholesterol/phospholipid ratios were significantly incre...

Full description

Bibliographic Details
Main Authors: Ludwig Amigo, Hegaly Mendoza, Silvana Zanlungo, Juan Francisco Miquel, Attilio Rigotti, Sergio González, Flavio Nervi
Format: Article
Language:English
Published: Elsevier 1999-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324585