High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers.

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers.

The role of Antibody-dependent cellular cytotoxicity (ADCC) responses in HIV-1 controllers is still unclear due to the heterogeneity of these patients. We analyzed 67 HIV-1 controllers and found significantly higher levels of ADCC antibodies in controllers versus viremic subjects (p = 0.017). Moreov...

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Bibliographic Details
Main Authors: Olivier Lambotte, Justin Pollara, Faroudy Boufassa, Christiane Moog, Alain Venet, Barton F Haynes, Jean-François Delfraissy, Asier Saez-Cirion, Guido Ferrari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781132?pdf=render

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http://europepmc.org/articles/PMC3781132?pdf=render

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