Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation

Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation

Abstract Rhinovirus (RV) infections are associated with asthma exacerbations. MicroRNA‐146a and microRNA‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that suppress signaling through the nuclear factor kappa B (NF‐κB) pathway and inhibit pro‐inflammatory chemokine production in primary human bronch...

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Bibliographic Details
Main Authors: Anet Laanesoo, Egon Urgard, Kapilraj Periyasamy, Martti Laan, Yury A. Bochkov, Alar Aab, Nathaniel Magilnick, Margus Pooga, James E. Gern, Sebastian L. Johnston, Jonathan M. Coquet, Mark P. Boldin, Jesper Wengel, Alan Altraja, Grazyna Bochenek, Bogdan Jakiela, Ana Rebane
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
asthma
bronchial epithelial cell
house dust mite
microRNA
neutrophils
noncoding RNA
Online Access:https://doi.org/10.1002/ctm2.427

Internet

https://doi.org/10.1002/ctm2.427

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