Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling

Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling

Neuroinflammation is characterized by activation of microglial cells, followed by production of nitric oxide (NO), which may have different outcomes on neurogenesis, favoring or inhibiting this process. In the present study, we investigated how the inflammatory mediator NO can affect proliferation o...

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Bibliographic Details
Main Authors: Bruno Pereira Carreira, Maria Inês Morte, Ana Isabel Santos, Ana Sofia Lourenço, António Francisco Ambrósio, Caetana M Carvalho, Inês M Araújo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Inflammation
Microglia
Neural Stem Cells
Nitric Oxide
cell proliferation.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00343/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00343/full

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