The Chemopreventive Effect of Tanacetum Polycephalum Against LA7-Induced Breast Cancer in Rats and the Apoptotic Effect of a Cytotoxic Sesquiterpene Lactone in MCF7 Cells: A Bioassay-Guided Approach

The Chemopreventive Effect of Tanacetum Polycephalum Against LA7-Induced Breast Cancer in Rats and the Apoptotic Effect of a Cytotoxic Sesquiterpene Lactone in MCF7 Cells: A Bioassay-Guided Approach

Background: Tanacetum polycephalum L. Schultz-Bip is a member of the Asteraceae family. This study evaluated the chemopreventive effect of a T. polycephalum hexane extract (TPHE) using in in vivo and in vitro models. Methods and Results: Five groups of rats: normal control, cancer control, TPHE low...

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Main Authors: Hamed Karimian, Mehran Fadaeinasab, Soheil Zorofchian Moghadamtousi, Maryam Hajrezaei, Maryam Zahedifard, Mahboubeh Razavi, Sher Zaman Safi, Syam Mohan, Shaden A.M. Khalifa, Hesham R. El-Seedi, Mahmood Amin Abdulla, Hapipah Mohd Ali, Mohamad Ibrahim Noordin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tanacetum polycephalum
Asteraceae
Sesquiterpene lactone
8β- hydroxyl- 4β, 15-dihydrozaluzanin C
Breast cancer
Apoptosis
LA7 cells
MCF7 cells
Online Access:http://www.karger.com/Article/FullText/430273

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http://www.karger.com/Article/FullText/430273

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